长爪沙鼠（Meriones unguiculatus）视网膜中的视锥细胞：一项免疫细胞化学和电生理学研究。

Cones in the retina of the Mongolian gerbil, Meriones unguiculatus: an immunocytochemical and electrophysiological study.

作者信息

Govardovskii V I, Röhlich P, Szél A, Khokhlova T V

机构信息

Institute of Evolutionary Physiology and Biochemistry, Leningrad, U.S.S.R.

出版信息

Vision Res. 1992 Jan;32(1):19-27. doi: 10.1016/0042-6989(92)90108-u.

DOI:10.1016/0042-6989(92)90108-u

PMID:1502806

Abstract

Immunocytochemistry revealed in the retina of the Mongolian gerbil three immunologically distinct photoreceptor cell types. Rods comprising about 87% of the total receptor population were selectively recognized by an antirhodopsin serum (AO). The most abundant cone type (11-13% of photoreceptors) was labeled by the monoclonal antibody COS-1, specific in mammals to the middle-to-long-wave sensitive cone visual pigments. A minor cone population (2.5-5% of the cones) reacted with the monoclonal antibody OS-2, shown earlier to bind to the blue cones in mammalian species. Color substitution experiments revealed on the ERG level a color discrimination capability which must be attributed to the cooperative activity of green-sensitive (COS-1 positive) and blue-sensitive (OS-2 positive) cones. We conclude that the Mongolian gerbil has a well developed cone system, and that it may possess dichromatic green-blue color vision.

摘要

免疫细胞化学显示，在蒙古沙鼠的视网膜中有三种免疫特性不同的光感受器细胞类型。抗视紫红质血清（AO）可选择性识别约占总感受器群体87%的视杆细胞。最丰富的视锥细胞类型（占光感受器的11 - 13%）由单克隆抗体COS - 1标记，该抗体在哺乳动物中对中长波敏感的视锥视觉色素具有特异性。少量的视锥细胞群体（占视锥细胞的2.5 - 5%）与单克隆抗体OS - 2发生反应，先前已证明该抗体可与哺乳动物物种中的蓝视锥细胞结合。颜色替代实验在视网膜电图水平上揭示了一种颜色辨别能力，这必须归因于绿色敏感（COS - 1阳性）和蓝色敏感（OS - 2阳性）视锥细胞的协同活动。我们得出结论，蒙古沙鼠具有发育良好的视锥系统，并且可能拥有二色性的绿蓝色视觉。