Hara Isao, Yao Akihisa, Muramaki Mototsugu, Hikosaka Satoko, Yamada Yuji, Kawabata Gaku, Kamidono Sadao
Division of Urology, Kobe University Graduate School of Medicine, Kobe, Japan.
Int J Urol. 2004 Apr;11(4):250-2. doi: 10.1111/j.1442-2042.2003.00774.x.
Bacillus Calmette-Guerin (BCG) instillation therapy is now a standard therapy for high-risk superficial bladder cancer patients. Although the complete response rate is approximately 70%, extra-vesical progression is sometimes observed. In particular, those patients who present a positive urinary cytology even after complete response from bladder lesion should be thoroughly examined. We present two cases of stromal invasion of the prostate after complete remission by BCG therapy of carcinoma in situ of the ureter and bladder found by transrectal prostate biopsy.
卡介苗（BCG）灌注疗法现已成为高危浅表性膀胱癌患者的标准治疗方法。尽管完全缓解率约为70%，但有时会观察到膀胱外进展。特别是那些即使膀胱病变完全缓解后尿细胞学检查仍呈阳性的患者，应进行全面检查。我们报告了2例经直肠前列腺活检发现输尿管和膀胱原位癌经卡介苗治疗完全缓解后发生前列腺间质浸润的病例。
