Wright Rollin M, Warpula Rick W
Division of Geriatrics, Department of Medicine, Rhode Island Hospital and Brown Medical School, Providence, RI 02903, USA.
J Am Podiatr Med Assoc. 2004 Mar-Apr;94(2):90-7. doi: 10.7547/87507315-94-2-90.
Adverse drug effects are common in elderly patients but can often be avoided. Judicious prescribing practices require the clinician to be aware of age-related changes in drug absorption, distribution, metabolism, and elimination. Clinicians may need to adjust drug dose, frequency, or the choice of drug altogether as they consider the physiologic changes of aging. This article reviews prescribing situations with elderly patients commonly encountered by the podiatric physician. Strategies for medication management are provided to minimize the risk of adverse drug events in the older patient.
药物不良反应在老年患者中很常见，但通常是可以避免的。明智的处方做法要求临床医生了解药物吸收、分布、代谢和排泄方面与年龄相关的变化。临床医生在考虑衰老的生理变化时，可能需要调整药物剂量、用药频率或完全改变药物选择。本文回顾了足病医生常见的老年患者处方情况。提供了药物管理策略，以尽量降低老年患者发生药物不良事件的风险。
