Giroux Marie-France, Baum Richard A, Soulen Michael C
Department of Radiology, Hospital of the University of Pennsylvania, 1 Silverstein, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA.
J Vasc Interv Radiol. 2004 Mar;15(3):289-91. doi: 10.1097/01.rvi.0000116190.44877.04.
Chemoembolization was performed in eight patients with liver metastasis from breast carcinoma. Five of eight patients had some radiographic regression of the liver tumors, one had stable liver disease, and two had disease progression. Two of four patients with pain showed clinical improvement of their symptoms. Only one patient with radiographic response or disease stabilization subsequently had intrahepatic progression (at 3 months). Five patients developed other metastasis, particularly brain metastasis, at a mean of 4.6 months after first chemoembolization (range, 2-12 months). All patients died within 13 months of treatment, with a mean survival of 49 months from primary diagnosis, 20 months from liver metastasis diagnosis, and 6 months from first chemoembolization.
对8例乳腺癌肝转移患者进行了化学栓塞治疗。8例患者中有5例肝肿瘤在影像学上有一定程度的消退，1例肝病稳定，2例病情进展。4例有疼痛的患者中有2例症状有临床改善。仅有1例影像学有反应或病情稳定的患者随后出现肝内进展（3个月时）。5例患者在首次化学栓塞治疗后平均4.6个月（范围2 - 12个月）出现其他转移，尤其是脑转移。所有患者在治疗后13个月内死亡，从原发诊断算起平均生存49个月，从肝转移诊断算起平均生存20个月，从首次化学栓塞治疗算起平均生存6个月。
