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[乳糜性腹水揭示非霍奇金淋巴瘤]

[Chylous ascitis revealing a non-Hodgkin lymphoma].

作者信息

Bachmeyer Claude, Henni Mehdi Alexandre, Blanc Anne-Sophie, Langman Benjamin, Kazerouni Firouze, Cadranel Jean-François

机构信息

Département de médecine interne, Centre hospitalier, Laënnec.

出版信息

Presse Med. 2004 Feb 14;33(3):167-9. doi: 10.1016/s0755-4982(04)98514-4.

Abstract

INTRODUCTION

Chylous ascitis is a rare form of ascitis, characterised by a milky, triglyceride-rich, liquid. It is due to an interruption in the lymphatic system due either to an obstruction or to a post-traumatic wound. We report a case of revealing a non-Hodgkin lymphoma.

OBSERVATION

A 71 Year-old man consulted for abdominal distension attributed to a chylous ascitis. Peripheral adenopathies were palpable. The abdominal scan revealed voluminous lumbar-aortal adenopathies. The diagnosis of grade IV (Ann Arbor classification) centro-follicular non-Hodgkin lymphoma was retained. The ascitis disappeared following chemotherapy.

COMMENTS

Chylous ascitis is an uncommon complication of lymphomas, although representing the main cause in adults in developed countries. The underlying mechanism is an obstruction to sub-diaphragmatic draining lymphatic due to lymphomatous infiltration. Hyperalimentation, a low, dietary restriction of long-chain triglycerides or peritoneovenous shuntings are ineffective.

CONCLUSION

Chylous ascitis is a rare complication of lymphomas, secondary to the obstruction of the abdominal draining lymphatics. Treatment is the same as that of a hematologic malignancy.

摘要

引言

乳糜性腹水是一种罕见的腹水形式,其特征为呈乳状、富含甘油三酯的液体。它是由于淋巴系统因阻塞或创伤后伤口而中断所致。我们报告一例以非霍奇金淋巴瘤为首发表现的病例。

病例

一名71岁男性因乳糜性腹水导致的腹胀前来就诊。可触及外周淋巴结肿大。腹部扫描显示大量腰主动脉旁淋巴结肿大。确诊为IV级(Ann Arbor分类)中心滤泡性非霍奇金淋巴瘤。化疗后腹水消失。

评论

乳糜性腹水是淋巴瘤的一种罕见并发症,尽管在发达国家是成人乳糜性腹水的主要病因。其潜在机制是淋巴瘤浸润导致膈下引流淋巴管阻塞。胃肠外营养、低脂肪饮食限制长链甘油三酯或腹腔静脉分流术均无效。

结论

乳糜性腹水是淋巴瘤的一种罕见并发症,继发于腹部引流淋巴管阻塞。治疗方法与血液系统恶性肿瘤相同。

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