Vassalotti Joseph A, Falk Abigail, Teodorescu Victoria, Uribarri Jaime
Nephrology Division, Box 1243, Mount Sinai School of Medicine, One East 100th Street, New York, NY 10029-6574, USA.
Mt Sinai J Med. 2004 Mar;71(2):94-102.
A majority of the quarter of a million end-stage renal disease patients nationwide are treated with hemodialysis. Important and frequent causes of morbidity and mortality, when they undergo this procedure, include vascular access infection and thrombosis associated with the use of catheters and, to a lesser extent, grafts. Therefore, an arteriovenous (AV) fistula is the preferred hemodialysis access. A multidisciplinary approach, including nephrologists, vascular surgeons, interventional radiologists, nurses, nephrology fellows, and nephrology physician assistants, meeting together weekly, should improve hemodialysis outcomes by promoting the use of AV fistulas. The specific roles of the interventional radiologist, vascular surgeon, nephrologist and other members of the multidisciplinary team are reviewed. Important additional components of this program are Doppler ultrasound for preoperative hemodialysis access vein mapping and screening techniques for early detection of arteriovenous graft stenosis. The use of arteriovenous fistulas in the Mount Sinai outpatient hemodialysis program has increased from 15% to 43% (p<0.001) and substantially limited catheter use since 1998, when the multidisciplinary program began.
全国25万终末期肾病患者中的大多数都接受血液透析治疗。在进行该治疗过程中,发病和死亡的重要且常见原因包括与导管使用相关的血管通路感染和血栓形成,以及程度较轻的与移植物相关的感染和血栓形成。因此,动静脉内瘘是首选的血液透析通路。一种多学科方法,包括肾病学家(肾脏科医生)、血管外科医生、介入放射科医生、护士、肾脏科研究员和肾脏科医师助理,每周共同会诊,应通过促进动静脉内瘘的使用来改善血液透析结果。文中回顾了介入放射科医生、血管外科医生、肾病学家以及多学科团队其他成员的具体职责。该项目的重要附加组成部分包括用于术前血液透析通路静脉造影的多普勒超声以及用于早期检测动静脉移植物狭窄的筛查技术。自1998年多学科项目启动以来,西奈山门诊血液透析项目中动静脉内瘘的使用比例已从15%增至43%(p<0.001),并且显著减少了导管的使用。