Ukarapol N, Lertprasertsuk N, Wongsawasdi L
Department of Paediatrics, Chiang Mai University, Chiang Mai 50200, Thailand.
Singapore Med J. 2004 Mar;45(3):121-4.
To study the utility of upper gastrointestinal endoscopy with biopsy in the evaluation of children with clinically-significant recurrent abdominal pain.
Over a three-month period, children with three or more episodes of upper abdominal pain that was severe enough to impair their normal activity and required medical attention were included in the study. After complete history, physical examination and basic investigations, upper gastrointestinal endoscopy with biopsy was performed in all patients.
Thirty-eight children were enrolled. Their average age was 10.5 years and 21 were female. Organic causes were identified in 44.7 percent of the cases, with Helicobacter pylori gastritis being the most common diagnosis (28.9 percent). No specific dyspeptic symptom was significantly associated with either organic cause of recurrent abdominal pain or Helicobacter pylori infection. Antral nodularity was the only endoscopic finding significantly associated with Helicobacter pylori infection (sensitivity 63.4 percent, specificity 85.2 percent). All patients improved after specific therapy was instituted.
The organic causes of recurrent abdominal pain in children have been increasingly identified in our hospital, a tertiary care centre in Northern Thailand. One of the most common causes found in this study was Helicobacter pylori infection. Upper endoscopy was very helpful in identifying the underlying pathology.
研究上消化道内镜检查及活检在评估有临床意义的复发性腹痛儿童中的作用。
在三个月的时间里，纳入有三次或更多次上腹部疼痛发作且严重到足以影响其正常活动并需要医疗关注的儿童。在完成病史采集、体格检查和基本检查后，对所有患者进行上消化道内镜检查及活检。
共纳入38名儿童。他们的平均年龄为10.5岁，其中21名是女性。44.7%的病例发现有器质性病因，幽门螺杆菌胃炎是最常见的诊断（28.9%）。没有特定的消化不良症状与复发性腹痛的器质性病因或幽门螺杆菌感染显著相关。胃窦结节是唯一与幽门螺杆菌感染显著相关的内镜表现（敏感性63.4%，特异性85.2%）。所有患者在采取特定治疗后病情均有改善。
在泰国北部的一家三级医疗中心——我们医院，越来越多地发现儿童复发性腹痛的器质性病因。本研究中发现的最常见病因之一是幽门螺杆菌感染。上消化道内镜检查对确定潜在病理状况非常有帮助。
