Rosenkrantz Wayne S
Animal Dermatology Clinic, Tustin, CA 92780, USA.
Vet Dermatol. 2004 Apr;15(2):90-8. doi: 10.1111/j.1365-3164.2004.00360.x.
Pemphigus is an autoimmune skin disease that can present in a variety of forms and can be a challenging disease to manage and treat. An overview of the different forms of pemphigus and diagnostics are discussed including pemphigus foliaceus (PF), pemphigus erythematosus (PE), panepidermal pustular pemphigus (PPP), pemphigus vulgaris (PV) and paraneoplastic pemphigus (PNP). Emphasis on therapy is presented. Included are the most current commonly used therapeutics (glucocorticoids, azathioprine, chlorambucil and tetracycline and niacinamide); current alternative therapeutics (cyclosporin and tacrolimus and mycophenolate mofetil) and additional alternative therapeutics (cyclophosphamide, chrysotherapy, dapsone, sulfasalazine and intravenous immunoglobulin (IVIG) therapy).
天疱疮是一种自身免疫性皮肤病，可呈现多种形式，是一种管理和治疗具有挑战性的疾病。本文讨论了天疱疮的不同形式及诊断方法，包括落叶型天疱疮（PF）、红斑型天疱疮（PE）、泛发性脓疱型天疱疮（PPP）、寻常型天疱疮（PV）和副肿瘤性天疱疮（PNP）。文中重点介绍了治疗方法。包括当前常用的治疗药物（糖皮质激素、硫唑嘌呤、苯丁酸氮芥、四环素和烟酰胺）；当前的替代治疗药物（环孢素、他克莫司和霉酚酸酯）以及其他替代治疗药物（环磷酰胺、金疗法、氨苯砜、柳氮磺胺吡啶和静脉注射免疫球蛋白（IVIG）疗法）。
