[用庆大霉素治疗杜氏肌营养不良症]
[Treatment of Duchenne muscular dystrophy with gentamicin].
作者信息
Matsuo Masafumi, Takeshima Yasuhiro, Yagi Mariko, Ishibashi Kazuto, Wada Hiroko
机构信息
Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Hyogo.
出版信息
No To Hattatsu. 2004 Mar;36(2):125-9.
PMID:15031986
Abstract
This article reviews the clinical application of gentamicin treatment for nonsense mutations. Since gentamicin is applied only for Duchenne muscular dystrophy caused by a nonsense mutation, genetic diagnosis of DMD is reviewed. Of the two reports describing gentamicin treatment of DMD, one concluded it to be effective, and the other to be ineffective.
摘要
本文综述了庆大霉素治疗无义突变的临床应用。由于庆大霉素仅用于由无义突变引起的杜氏肌营养不良症，因此对杜氏肌营养不良症的基因诊断进行了综述。在两篇描述庆大霉素治疗杜氏肌营养不良症的报告中，一篇认为其有效，另一篇则认为无效。
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