Ginopoulos P V, Michail G D, Kourounis G S
Department of Medical Oncology, Agios Andreas Hospital, Greece.
Eur J Gynaecol Oncol. 2004;25(2):261-3.
Despite its infrequency, pregnancy associated breast cancer implies multiple therapeutic dilemmas. Our patient, a 32-year-old Caucasian, gravida 2, para 2, was diagnosed with cancer of the left breast in the 19th week of gestation. Shortly after she underwent quadrantectomy plus axillary lymph node dissection. Chemotherapy was initiated in the 22(+6) week--four cycles of a combination of endoxan, farmorubicin, and fluorouracil. The patient gave birth in the 35(+6) week to a healthy baby with no apparent malformations. During puerperium she received two more cycles of chemotherapy. She is currently undergoing radiotherapy with tangential fields. Although it is too early to draw conclusions, the malignancy seems to be inactive.
尽管妊娠相关乳腺癌并不常见，但它意味着多种治疗困境。我们的患者是一名32岁的白种人，孕2产2，在妊娠第19周被诊断为左乳腺癌。不久后她接受了象限切除术加腋窝淋巴结清扫术。化疗于第22（+6）周开始——采用环磷酰胺、表柔比星和氟尿嘧啶联合方案进行四个周期的化疗。患者在第35（+6）周产下一名健康婴儿，无明显畸形。产褥期她又接受了两个周期的化疗。她目前正在接受切线野放疗。虽然现在得出结论还为时过早，但恶性肿瘤似乎已无活性。
