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住院辩证行为疗法治疗边缘型人格障碍的有效性:一项对照试验。

Effectiveness of inpatient dialectical behavioral therapy for borderline personality disorder: a controlled trial.

作者信息

Bohus Martin, Haaf Brigitte, Simms Timothy, Limberger Matthias F, Schmahl Christian, Unckel Christine, Lieb Klaus, Linehan Marsha M

机构信息

Department of Psychiatry and Psychotherapy with Polyclinic, Albert-Ludwig-University of Freiburg, Medical School, Hauptstrasse 5, D-79104 Freiburg, Germany.

出版信息

Behav Res Ther. 2004 May;42(5):487-99. doi: 10.1016/S0005-7967(03)00174-8.

Abstract

Dialectical Behavioral Therapy (DBT) was initially developed and evaluated as an outpatient treatment program for chronically suicidal individuals meeting criteria for borderline personality disorder (BPD). Within the last few years, several adaptations to specific settings have been developed. This study aims to evaluate a three-month DBT inpatient treatment program. Clinical outcomes, including changes on measures of psychopathology and frequency of self-mutilating acts, were assessed for 50 female patients meeting criteria for BPD. Thirty-one patients had participated in a DBT inpatient program, and 19 patients had been placed on a waiting list and received treatment as usual in the community. Post-testing was conducted four months after the initial assessment (i.e. four weeks after discharge for the DBT group). Pre-post-comparison showed significant changes for the DBT group on 10 of 11 psychopathological variables and significant reductions in self-injurious behavior. The waiting list group did not show any significant changes at the four-months point. The DBT group improved significantly more than participants on the waiting list on seven of the nine variables analyzed, including depression, anxiety, interpersonal functioning, social adjustment, global psychopathology and self-mutilation. Analyses based on Jacobson's criteria for clinically relevant change indicated that 42% of those receiving DBT had clinically recovered on a general measure of psychopathology. The data suggest that three months of inpatient DBT treatment is significantly superior to non-specific outpatient treatment. Within a relatively short time frame, improvement was found across a broad range of psychopathological features. Stability of the recovery after one month following discharge, however, was not evaluated and requires further study.

摘要

辩证行为疗法(DBT)最初是作为一种门诊治疗方案而开发和评估的,用于治疗符合边缘性人格障碍(BPD)标准的慢性自杀倾向个体。在过去几年中,针对特定环境开发了几种适应性方案。本研究旨在评估一个为期三个月的DBT住院治疗方案。对50名符合BPD标准的女性患者评估了临床结果,包括精神病理学指标的变化和自我伤害行为的频率。31名患者参加了DBT住院治疗方案,19名患者被列入等待名单并在社区接受常规治疗。在初始评估四个月后(即DBT组出院四周后)进行了后测。前后比较显示,DBT组在11个精神病理学变量中的10个上有显著变化,自我伤害行为显著减少。等待名单组在四个月时未显示任何显著变化。在分析的九个变量中的七个上,DBT组的改善明显超过等待名单上的参与者,包括抑郁、焦虑、人际功能、社会适应、整体精神病理学和自我伤害。基于雅各布森临床相关变化标准的分析表明,接受DBT治疗的患者中有42%在精神病理学综合测量指标上实现了临床康复。数据表明,三个月的DBT住院治疗明显优于非特异性门诊治疗。在相对较短的时间内,在广泛的精神病理学特征方面都有改善。然而,出院后一个月康复的稳定性未进行评估,需要进一步研究。

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