Zou Guangyong
Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada.
Am J Epidemiol. 2004 Apr 1;159(7):702-6. doi: 10.1093/aje/kwh090.
Relative risk is usually the parameter of interest in epidemiologic and medical studies. In this paper, the author proposes a modified Poisson regression approach (i.e., Poisson regression with a robust error variance) to estimate this effect measure directly. A simple 2-by-2 table is used to justify the validity of this approach. Results from a limited simulation study indicate that this approach is very reliable even with total sample sizes as small as 100. The method is illustrated with two data sets.
相对风险通常是流行病学和医学研究中感兴趣的参数。在本文中，作者提出了一种改进的泊松回归方法（即具有稳健误差方差的泊松回归）来直接估计这种效应量度。使用一个简单的2×2表格来证明该方法的有效性。一项有限的模拟研究结果表明，即使总样本量小至100，该方法也非常可靠。用两个数据集对该方法进行了说明。
