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蕈样肉芽肿患者的迟发型超敏反应。

Delayed-type hypersensitivity in patients with mycosis fungoides.

作者信息

van der Harst-Oostveen C J, van Vloten W A

出版信息

Dermatologica. 1978;157(3):129-35. doi: 10.1159/000250818.

Abstract

Cell-mediated immune reactivity was studied in 23 patients with mycosis fungoides and Sézary's syndrome by a semi-quantitative 2,4-dinitrochlorobenzene (DNCB) sensibilization test and the reaction to intracutaneous microbial antigens. Anergy to DNCB was observed in 8 patients, 5 had a markedly depressed DNCB score, 6 showed negative reactions to the microbial antigens. A defect in antigen recognition is suggested.

摘要

通过半定量2,4-二硝基氯苯(DNCB)致敏试验和对皮内微生物抗原的反应,研究了23例蕈样肉芽肿和塞扎里综合征患者的细胞介导免疫反应性。8例患者对DNCB无反应,5例患者的DNCB评分明显降低,6例患者对微生物抗原呈阴性反应。提示存在抗原识别缺陷。

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