Sunenshine Rebecca H, Liedtke Laura A, Jernigan Daniel B, Strausbaugh Larry J
Division of Infectious Diseases, Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Clin Infect Dis. 2004 Apr 1;38(7):934-8. doi: 10.1086/382358. Epub 2004 Mar 15.
The Infectious Diseases Society of America Emerging Infections Network (EIN) surveyed its members to characterize antimicrobial restriction policies in their hospitals and the involvement of infectious diseases consultants in this process. Of the 502 respondents (73%), 250 (50%) indicated that their hospital pharmacies would not dispense certain antimicrobials without approval of infectious diseases consultants. Moreover, 89% agreed that infectious diseases consultants need to be directly involved in the approval process. At hospitals with control policies, commonly restricted agents included lipid formulations of amphotericin B, carbapenems, fluoroquinolones, piperacillin-tazobactam, and vancomycin. Only 46 EIN members (18%) reported remuneration of infectious diseases consultants for participation in the approval process. Pediatric infectious diseases consultants were more likely to practice in hospitals with restriction policies than were adult infectious diseases consultants (64% vs. 45%; P<.001). Similarly, teaching hospitals were more likely to have antimicrobial-control policies than were nonteaching facilities (60% vs. 17%; P<.001).
美国传染病学会新发感染网络(EIN)对其成员进行了调查,以了解其所在医院的抗菌药物限制政策以及传染病顾问在此过程中的参与情况。在502名受访者(占73%)中,250人(占50%)表示,其所在医院的药房在未经传染病顾问批准的情况下不会发放某些抗菌药物。此外,89%的受访者同意传染病顾问需要直接参与审批过程。在实施控制政策的医院中,常见的受限药物包括两性霉素B脂质体、碳青霉烯类、氟喹诺酮类、哌拉西林-他唑巴坦和万古霉素。只有46名EIN成员(占18%)报告称传染病顾问参与审批过程有报酬。与成人传染病顾问相比,儿科传染病顾问更有可能在实施限制政策的医院工作(64%对45%;P<0.001)。同样,教学医院比非教学机构更有可能制定抗菌药物控制政策(60%对17%;P<0.001)。