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[经动脉灌注抗癌药物(顺铂和吡柔比星)及球囊导管阻塞髂内动脉后完全缓解的膀胱癌:一例报告]

[A bladder cancer with complete remission after arterial infusion of anti-cancer agents (CDDP and THP) and balloon-catheter occlusion of the internal iliac artery: a case report].

作者信息

Hosoya Y, Soh S, Honda M, Takasaki E

机构信息

Department of Urology, Dokkyo University School of Medicine, Tochigi, Japan.

出版信息

Gan To Kagaku Ryoho. 1992 Aug;19(9):1395-7.

PMID:1503490
Abstract

The case was a 63-year-old male with the chief complaint of hematuria. A local doctor made the diagnosis of a bladder tumor (egg-sized) on the basis of the results of ultrasonography. CT-scan and cystoscopy. He was thus referred to our Department for treatment. Histopathological study of the biopsied tumor specimen revealed that the tumor was a squamous cell carcinoma. The bilateral internal iliac arteries were occluded for 48 hours, and 100 mg of CDDP and 40 mg of THP were arterially infused. After 7 days, hematuria disappeared, as did the tumor 5 weeks after treatment. No malignancy was noted from histological examination of a biopsy specimen obtained from the cured cancer region using a cystoscope. Since then, there was no recurrence for 12 months. Thus, this approach is thought to be an effective treatment for primary bladder cancer.

摘要

该病例为一名63岁男性,主要症状为血尿。当地医生根据超声、CT扫描和膀胱镜检查结果诊断为膀胱肿瘤(鸡蛋大小)。因此,他被转诊至我院接受治疗。对活检肿瘤标本进行组织病理学研究发现,该肿瘤为鳞状细胞癌。双侧髂内动脉闭塞48小时,动脉内注入100毫克顺铂和40毫克吡柔比星。7天后,血尿消失,治疗5周后肿瘤也消失。使用膀胱镜从治愈的癌区获取的活检标本经组织学检查未发现恶性肿瘤。从那时起,12个月内未出现复发。因此,这种方法被认为是原发性膀胱癌的有效治疗方法。

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