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鞍内动脉瘤与分泌生长激素的垂体大腺瘤。病例报告。

Intrasellar aneurysm and a growth hormone-secreting pituitary macroadenoma. Case report.

作者信息

Sade Burak, Mohr Gérard, Tampieri Donatella, Rizzo Arthur

机构信息

Division of Neurosurgery, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada.

出版信息

J Neurosurg. 2004 Mar;100(3):557-9. doi: 10.3171/jns.2004.100.3.0557.

Abstract

An aneurysm completely included within a pituitary adenoma that lies inside the sella turcica is rare and challenging from both a diagnostic and treatment viewpoint. A 39-year-old woman presented with symptoms and signs of acromegaly. Magnetic resonance imaging revealed a pituitary macroadenoma, which was associated with an intrasellar aneurysm. Digital subtraction angiography confirmed the presence of the cavernous carotid artery aneurysm. Complete endovascular obliteration of the aneurysm was achieved using Guglielmi Detachable Coils and the patency of the internal carotid artery was maintained. The pituitary adenoma was resected subtotally via a transsphenoidal microsurgical approach 8 months later. Preoperative detection of a coexisting intrasellar aneurysm in a patient with a pituitary adenoma is mandatory to avoid life-threatening hemorrhagic complications. Endovascular coil placement is an effective treatment option when performed before the transsphenoidal removal of the adenoma.

摘要

完全包含在蝶鞍内垂体腺瘤内的动脉瘤非常罕见,从诊断和治疗角度来看都具有挑战性。一名39岁女性出现肢端肥大症的症状和体征。磁共振成像显示垂体大腺瘤,伴有鞍内动脉瘤。数字减影血管造影证实存在海绵窦段颈内动脉瘤。使用 Guglielmi 可脱卸弹簧圈实现了动脉瘤的完全血管内闭塞,并保持了颈内动脉的通畅。8个月后通过经蝶窦显微手术入路次全切除垂体腺瘤。垂体腺瘤患者术前必须检测并存的鞍内动脉瘤,以避免危及生命的出血并发症。在经蝶窦切除腺瘤之前进行血管内弹簧圈置入是一种有效的治疗选择。

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