Zawistowski Christine A, DeVita Michael A
University of Pittsburgh School of Medicine, Department of Critical Care Medicine, PA 15213, USA.
J Intensive Care Med. 2003 Jul-Aug;18(4):189-97. doi: 10.1177/0885066603253314.
Organ transplantation is one of the groundbreaking achievements in medicine in the 20th century. In the early days of transplantation, organs were obtained from non-heartbeating (NHB) cadavers. With time, better options for organ sources became available (for example, living-related and "brain dead" donors), and the practice of obtaining organs from NHB cadavers fell out of favor. Improvements in the field of transplantation have led to an increased demand for organs. Various strategies have been employed recently to increase the supply, one of them being non-heartbeating organ donation (NHBOD). NHBOD can take place in controlled or uncontrolled circumstances. Recently, national organizations have supported and proposed guidelines for NHBOD and to aid clinicians in identifying potential donors. Outcomes of organs obtained from NHB cadavers are comparable to those obtained from heartbeating donors. The practice of NHBOD is increasing and has proven that it can contribute to increasing organ availability.
器官移植是20世纪医学领域的开创性成就之一。在移植早期,器官取自非心跳死亡(NHB)的尸体。随着时间推移,有了更好的器官来源选择(例如,亲属活体和“脑死亡”供体),从NHB尸体获取器官的做法不再受欢迎。移植领域的进步导致对器官的需求增加。最近采用了各种策略来增加供应,其中之一是非心跳器官捐献(NHBOD)。NHBOD可在可控或不可控的情况下进行。最近,国家组织支持并提出了NHBOD指南,以帮助临床医生识别潜在供体。从NHB尸体获取的器官的结果与从心跳供体获取的器官相当。NHBOD的做法正在增加,并已证明它有助于增加器官的可获得性。