Chen Tainsong, Chen Pei-Jarn, Fung Chia-Shiung, Lin Chi-Jeng, Yao Wei-Jen
Institute of Biomedical Engineering, National Cheng-Kung UniversityTainan 70101,Taiwan.
Med Eng Phys. 2004 Mar;26(2):141-5. doi: 10.1016/j.medengphy.2003.09.001.
Bone mineral density (BMD) is used as a clinical estimate of the risk of fracture. Ultrasound provides an alternative or complement to X-ray based methods of bone densitometry for determining BMD. Among ultrasonic characteristics, the speed of sound (SOS) is a useful tool for assessment of osteoporosis because, as recently reported, it represents a combination of density and compressibility of bone tissue. Thus, it might provide better information on bone quality to estimate the fracture risk. In this paper, a dual-transducer ultrasound technique was employed to measure the mean ultrasound propagation speed of the cortical layer as well as the cancellous layer at the tibia shaft. Encouraging results from 18 outpatients showed a high correlation (r = 0.93) between measurements of BMD and those from dual energy X-ray absorptiometry (DEXA).
骨密度(BMD)被用作骨折风险的临床评估指标。超声为基于X射线的骨密度测定方法提供了一种替代或补充手段,用于测定骨密度。在超声特性中,声速(SOS)是评估骨质疏松症的有用工具,因为正如最近报道的那样,它代表了骨组织密度和可压缩性的综合指标。因此,它可能在估计骨折风险方面提供有关骨质量的更好信息。在本文中,采用双换能器超声技术测量胫骨干皮质层以及松质层的平均超声传播速度。18名门诊患者的令人鼓舞的结果显示,骨密度测量值与双能X线吸收法(DEXA)测量值之间具有高度相关性(r = 0.93)。