用环孢素A对自身免疫性神经疾病进行免疫干预。

Immunointervention with cyclosporin A in autoimmune neurological disorders.

作者信息

Tindall R S

机构信息

Department of Neurology, Southwestern Medical School, University of Texas, Dallas.

出版信息

J Autoimmun. 1992 Apr;5 Suppl A:301-13. doi: 10.1016/0896-8411(92)90048-u.

DOI:10.1016/0896-8411(92)90048-u

PMID:1503626

Abstract

Cyclosporin A has proven a remarkably effective compound in suppressing disease activity in a number of animal models of autoimmune neurological disorders. During the last decade a number of controlled clinical trials have been carried out in human neurological disorders which are considered to be immune-mediated. The results of those trials are reviewed.

摘要

环孢菌素A已被证明是一种非常有效的化合物，可抑制多种自身免疫性神经疾病动物模型中的疾病活动。在过去十年中，已经对一些被认为是免疫介导的人类神经疾病进行了多项对照临床试验。本文对这些试验的结果进行了综述。