Cunha Sérgio C, Dourado Inês
London School of Hygiene and Tropical Medicine, Infectious Diseases and Epidemiology Unit, 2 Taviton Street, WC1H 0BT, London, UK.
Health Policy. 2004 Mar;67(3):323-8. doi: 10.1016/j.healthpol.2003.07.008.
Vaccination is unquestionably a very important tool for disease control. However, vaccines can cause adverse events that may damage the public trust. In recent experience in Brazil, the implementation of mass campaigns with MMR (measles, mumps, rubella) vaccine was associated with outbreaks of vaccine adverse events. The decision-making process regarding the continuation of the use of this vaccine proceeded in the context of uncertainties, fears and contradictions between information from the scientific literature and data generated by a post-licensure monitoring. This experience showed how important is to have a critical view of previous recommendations and to get local data addressing questions to guide the decision making process.
疫苗接种无疑是疾病防控的一项非常重要的工具。然而，疫苗可能会引发不良事件，这可能损害公众信任。在巴西最近的经历中，大规模接种麻疹、腮腺炎、风疹（MMR）疫苗的活动与疫苗不良事件的爆发有关。关于继续使用该疫苗的决策过程是在科学文献信息与上市后监测所产生的数据之间存在不确定性、恐惧和矛盾的背景下进行的。这一经历表明，对先前的建议持有批判性观点以及获取解决问题的本地数据以指导决策过程是多么重要。
