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腹部和盆腔靶区的立体定向增强放疗。

Stereotactic boost irradiation for targets in the abdomen and pelvis.

作者信息

Wulf Jörn, Hädinger Ulrich, Oppitz Ulrich, Thiele Wibke, Flentje Michael

机构信息

Department of Radiotherapy, University of Würzburg, Josef-Schneider-Strasse 11, D-97080 Würzburg, Germany.

出版信息

Radiother Oncol. 2004 Jan;70(1):31-6. doi: 10.1016/j.radonc.2003.10.013.

Abstract

Based on the experience of stereotactic irradiation of lung and liver tumors the feasibility of stereotactic boost irradiation to abdominal and pelvic tumors was evaluated. Twenty-one patients with inoperable tumors received a stereotactic boost of 2-3 x 5Gy/PTV-enclosing-100% isodose with normalization to 150% at the isocenter after normofractionated irradiation of 45-50.4Gy. Actuarial local control (16/21 targets) was 96/70% after 12 and 24 months. Treatment was feasible and well tolerated.

摘要

基于肺部和肝脏肿瘤立体定向放射治疗的经验,对腹部和盆腔肿瘤进行立体定向追加放射治疗的可行性进行了评估。21例无法手术的肿瘤患者在接受45-50.4Gy常规分割照射后,接受了2-3次5Gy/PTV-包绕-100%等剂量线的立体定向追加照射,等中心剂量归一至150%。12个月和24个月时的精算局部控制率(16/21个靶区)分别为96%/70%。治疗可行且耐受性良好。

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