Kwak Y L, Oh Y J, Jung S M, Yoo K J, Lee J H, Hong Y W
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
Eur J Cardiothorac Surg. 2004 Apr;25(4):572-7. doi: 10.1016/j.ejcts.2004.01.005.
Hemodynamic derangement during displacement of beating heart in off-pump coronary artery bypass graft (OPCAB) surgery might be related with right ventricular (RV) dysfunction. We evaluated RV function and hemodynamic alterations using a thermodilution pulmonary artery catheter.
The study included 30 patients undergoing OPCAB, using single pericardial suture and tissue stabilizer. A thermodilution pulmonary artery catheter for continuous monitoring of the cardiac output (CO), right ventricular ejection fraction (RVEF) and RV volume was inserted before anesthesia. The hemodynamic variables were measured after the induction of anesthesia, 5 min after the heart was positioned for each coronary anastomosis and after the sternum was closed.
There was no significant change in the RVEF and cardiac index during anastomosis of the left anterior descending artery and right coronary artery. However, the significantly reduced RVEF accompanied by an increase in RV afterload and decrease in the CO was observed during anastomosis of the obtuse marginal (OM) artery. RV volumes did not significantly change during anastomoses, though the right atrial pressure increased during anastomoses of all coronary arteries.
The displacement of beating heart for positioning during anastomosis of the graft to OM artery caused significant derangement of RV function and decrease in CO. A thermodilution catheter continuously measuring the CO and RVEF was useful to monitor the change in RV function and volume during OPCAB.
非体外循环冠状动脉搭桥术(OPCAB)中跳动心脏移位期间的血流动力学紊乱可能与右心室(RV)功能障碍有关。我们使用热稀释肺动脉导管评估了右心室功能和血流动力学改变。
本研究纳入了30例行OPCAB的患者,采用单心包缝合和组织稳定器。在麻醉前插入一根用于连续监测心输出量(CO)、右心室射血分数(RVEF)和右心室容积的热稀释肺动脉导管。在麻醉诱导后、每次冠状动脉吻合心脏定位5分钟后以及胸骨关闭后测量血流动力学变量。
在左前降支和右冠状动脉吻合期间,RVEF和心脏指数无显著变化。然而,在钝缘支(OM)动脉吻合期间,观察到RVEF显著降低,同时右心室后负荷增加,CO降低。尽管在所有冠状动脉吻合期间右心房压力均升高,但右心室容积在吻合期间无显著变化。
在将移植物吻合至OM动脉期间,跳动心脏的定位移位导致右心室功能显著紊乱和CO降低。一根连续测量CO和RVEF的热稀释导管有助于监测OPCAB期间右心室功能和容积的变化。