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伴有抗中枢神经系统和抗胸腺抗体的视神经脊髓炎谱系疾病和胸腺瘤

Devic disease and thymoma with anti-central nervous system and antithymus antibodies.

作者信息

Antoine J C, Camdessanché J P, Absi L, Lassablière F, Féasson L

机构信息

Service de Neurologie and EA 3062, Etablissement Français du Sang and EA 3062, France.

出版信息

Neurology. 2004 Mar 23;62(6):978-80. doi: 10.1212/01.wnl.0000115168.73299.88.

DOI:10.1212/01.wnl.0000115168.73299.88
PMID:15037705
Abstract

A patient with myasthenia gravis and thymoma developed neuromyelitis optica (NMO) and necrotizing myositis 4 months after treatment of the tumor. Antibodies reacting with the CNS and thymic epithelial cells were detected in the serum during the acute phase of NMO, suggesting that the NMO was linked to the thymoma.

摘要

一名患有重症肌无力和胸腺瘤的患者在肿瘤治疗4个月后发生了视神经脊髓炎(NMO)和坏死性肌炎。在NMO急性期血清中检测到与中枢神经系统和胸腺上皮细胞发生反应的抗体,提示NMO与胸腺瘤有关。

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