Gray M J, Kirberger R M, Spotswood T C
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.
J S Afr Vet Assoc. 2003 Dec;74(4):104-10. doi: 10.4102/jsava.v74i4.520.
The Boerboel is a South African large-breed dog resembling a Bullmastiff. The records of Onderstepoort Veterinary Academic Hospital were searched for dogs that had presented, between 1998 and 2003, with symptoms indicative of wobbler syndrome and had undergone survey radiographic and myelographic studies. Ten cases fitted the inclusion criteria. Dogs presented within the first 2 years of life, often with acute onset of symptoms. All presented with pelvic limb and 6 with concomitant thoracic limb ataxia or paresis. Treatment varied and included none (4), prednisolone (2), and dorsal laminectomy (2). Two dogs were euthanased at the time of diagnosis. The breed appears to be affected with a form of spondylomyelopathy that comprises bony malformation of cervical and/or thoracic vertebrae. In 8 dogs, malformations were evident on survey radiographs and were characterised by enlarged, irregular articular facets and associated medial deviation of the pedicles. These changes resulted in axial compression of the spinal cord best seen on ventrodorsal or dorsoventral myelographic studies. Multiple vertebrae were affected in some dogs and lesions were not confined to the caudal area of the cervical spine. Three dogs were alive and without symptoms at follow-up. Four were euthanased as a result of the disease and 1 died as a result of post-operative complications. Two additional dogs presenting with wobbler clinical signs are also described. One had medial deviation of the T5 and T6 caudal pedicles and 1 dog suffered from multiple cervical articular facet synovial cysts.
布尔博厄犬是一种类似于斗牛獒的南非大型犬。对翁德斯普特兽医学院附属医院的记录进行了检索,查找在1998年至2003年间出现摇晃综合征症状并接受了X线平片和脊髓造影检查的犬只。有10例符合纳入标准。犬只在出生后的头2年内发病,症状通常急性发作。所有犬只均出现后肢共济失调或麻痹,6只同时伴有前肢共济失调或麻痹。治疗方法各异,包括未治疗(4只)、泼尼松龙治疗(2只)和椎板切除术(2只)。2只犬在诊断时实施了安乐死。该品种似乎患有一种脊椎脊髓病,表现为颈椎和/或胸椎的骨质畸形。8只犬在X线平片上可见畸形,其特征为关节面增大、不规则以及椎弓根内侧偏移。这些改变导致脊髓受到轴向压迫,在腹背位或背腹位脊髓造影检查中最为明显。一些犬有多节段椎体受累,病变并不局限于颈椎尾端区域。3只犬在随访时存活且无症状。4只因该病实施了安乐死,1只因术后并发症死亡。还描述了另外2只出现摇晃综合征临床症状的犬只。1只犬的第5和第6胸椎尾侧椎弓根内侧偏移,另1只犬患有多个颈椎关节面滑膜囊肿。