Spicer R D
Leeds General Infirmary, UK.
Br J Cancer Suppl. 1992 Aug;18:S80-3.
Thirty-five different soft tissue tumours occurring in the first month of life are described and classified into five Clinical Groups. A. Excellent prognosis with no treatment or simple surgical excision. B. Good prognosis. Treatment depends upon anatomical site. C. Good prognosis. Treatment usually surgical but chemotherapy may be indicated in certain situations. D. Intermediate prognosis. Treatment as for older child, usually surgery or chemotherapy. E. Poor prognosis. Treatment palliative or experimental. The relatively good prognosis of tumours in this age group and the importance of avoiding over-treatment are emphasised. Treatment guidelines are given and the value of obtaining tissue for biological studies to improve our understanding of these rare tumours is stressed.
本文描述了35种在出生后第一个月出现的不同软组织肿瘤,并将其分为五个临床组。A组:预后良好,无需治疗或仅需简单手术切除。B组:预后良好。治疗取决于解剖部位。C组:预后良好。通常采用手术治疗,但在某些情况下可能需要化疗。D组:预后中等。治疗方法与大龄儿童相同,通常为手术或化疗。E组:预后不良。采用姑息治疗或试验性治疗。强调了该年龄组肿瘤相对良好的预后以及避免过度治疗的重要性。给出了治疗指南,并强调了获取组织进行生物学研究以增进我们对这些罕见肿瘤理解的价值。