Donnio A, Buestel C, Ventura E, Merle H
Service d'Ophtalmologie, CHU, Hôpital Pierre Zobda-Quitman, BP 632, 97261 Fort de France.
J Fr Ophtalmol. 2004 Mar;27(3):285-90. doi: 10.1016/s0181-5512(04)96132-3.
We report a case of cat-scratch disease neuroretinitis for which systemic and ocular investigations proved the responsibility of Bartonella henselae. An 11-year-old boy was referred to the hospital in November 2002 for severe visual loss in the left eye over the preceding 2 weeks. At the same time, he also developed a flu-like illness. The best corrected acuity in the left eye was counting fingers at 30 cm. Posterior segment examination on the left eye showed an optic disk edema with papillary and peripapillary hemorrhages and serous retinal detachment, mild vitreous inflammation, and two little perivascular white spots. The medical history was unremarkable except for a cat scratch on his left forearm 2 months before. Four weeks of antibiotic therapy including oral rifampin and doxycycline was used. Bartonella henselae immunoglobulin M were first detected with Bartonella henselae immunoglobulin G testing negative at this time. A 3-week serum showed immunoglobulin M seroreversion, while Bartonella henselae immunoglobulin G appeared. Other causes of optic disk edema with macular star were excluded by biological data. Bartonella antibodies to both Bartonella henselae and Bartonella clarridgeiae were detected in the cat. Ophthalmic follow-up showed progressive resorption of the neuroretinitis and the visual acuity increased to 5/10. The significance of this case report lies in the reminder that this pathology can be the cause of neuroretinitis; the prognosis can be improved by earlier treatment.
我们报告一例猫抓病性视神经视网膜炎病例,全身及眼部检查证实为汉赛巴尔通体所致。一名11岁男孩于2002年11月因前2周左眼严重视力丧失被转诊至医院。同时,他还出现了类似流感的疾病。左眼最佳矫正视力为30厘米处数指。左眼后段检查显示视盘水肿,伴有视乳头及视乳头周围出血和浆液性视网膜脱离,轻度玻璃体炎症,以及两个小的血管周围白色斑点。病史无异常,仅2个月前左前臂有猫抓痕。采用了包括口服利福平和多西环素在内的四周抗生素治疗。此时首次检测到汉赛巴尔通体免疫球蛋白M,而汉赛巴尔通体免疫球蛋白G检测为阴性。3周后的血清显示免疫球蛋白M血清学逆转,同时出现了汉赛巴尔通体免疫球蛋白G。通过生物学数据排除了其他导致视盘水肿伴黄斑星的原因。在猫身上检测到了针对汉赛巴尔通体和克拉瑞杰巴尔通体的巴尔通体抗体。眼科随访显示视神经视网膜炎逐渐吸收,视力提高到了5/10。本病例报告的意义在于提醒人们,这种病理情况可能是视神经视网膜炎的病因;早期治疗可改善预后。