Jardine A G, Geddes C C
Renal Transplant Unit, Glasgow, UK.
Transplant Proc. 2004 Mar;36(2 Suppl):139S-142S. doi: 10.1016/j.transproceed.2003.12.052.
The renal transplant unit in Glasgow has performed over 1500 renal transplants since the introduction of cyclosporine (CyA) in 1984. We extracted data on all renal transplants from cadaveric donors, where the recipient received primary immunosuppression with CyA, between 1984 and 2002. A total of 1262 transplants were analyzed in four eras (1984-1988, 1989-1992, 1993-1996, 1997-2002). Over this time period we observed progressive improvement in graft and patient survival, with the clearest improvements coinciding with the introduction of the Neoral formulation of CyA.
自1984年引入环孢素（CyA）以来，格拉斯哥的肾移植单位已进行了1500多例肾移植手术。我们提取了1984年至2002年间所有来自尸体供体的肾移植数据，这些受者接受了以CyA为主的免疫抑制治疗。在四个时期（1984 - 1988年、1989 - 1992年、1993 - 1996年、1997 - 2002年）共分析了1262例移植手术。在此期间，我们观察到移植物和患者存活率逐步提高，最显著的改善与Neoral剂型的CyA引入相吻合。
