Wang Huann-Sheng, Lin Jen-Kou, Mou Chih-Yuan, Lin Tzu-Chen, Chen Wei-Shone, Jiang Jeng-Kae, Yang Shung-Haur
Division of Colon and Rectal Surgery, Department of Surgery, Veterans General Hospital-Taipei, National Yang-Ming University School of Medicine, Taipei, Taiwan, Republic of China.
Am J Surg. 2004 Apr;187(4):497-500. doi: 10.1016/j.amjsurg.2003.12.028.
The long-term prognosis of patients with colon cancer is dependent on many factors. The aim of this retrospective study was to assess the long-term prognosis of patients with obstructing carcinoma of the right colon.
From 1981 to 1988, 256 patients at the Veterans General Hospital-Taipei who were status postcurative resection of right colon adenocarcinoma were classified as obstruction group (n = 35) or nonobstruction group (n = 221) as appropriate.
Analysis revealed no differences in age, sex, tumor location, or stage (P >0.05) between the two groups. However, the overall and distant recurrence rates were significant higher in obstructed patients than in nonobstructed patients. Further, long-term crude and cancer-specific survival rates were significantly lower in obstructed patients when examining either overall patient outcome or stage-matched outcomes. Multivariate analysis demonstrated that obstruction and tumor stage were both independent prognostic factors.
Obstruction status was an independent prognostic factor for patients with right colon carcinoma. The long-term prognosis of patients with obstructing carcinoma of the right colon was poor.
结肠癌患者的长期预后取决于多种因素。本回顾性研究的目的是评估右半结肠癌梗阻性癌患者的长期预后。
1981年至1988年，台北荣民总医院256例接受右半结肠腺癌根治性切除术后的患者，根据情况分为梗阻组（n = 35）或非梗阻组（n = 221）。
分析显示两组在年龄、性别、肿瘤位置或分期方面无差异（P>0.05）。然而，梗阻患者的总体复发率和远处复发率显著高于非梗阻患者。此外，在检查总体患者结局或分期匹配结局时，梗阻患者的长期粗生存率和癌症特异性生存率显著较低。多因素分析表明，梗阻和肿瘤分期均为独立的预后因素。
梗阻状态是右半结肠癌患者的独立预后因素。右半结肠癌梗阻性癌患者的长期预后较差。
