Mostella Jenester, Pieroni Robert, Jones Richard, Finch Christopher K
Department of Clinical Pharmacy, Druid City Hospital, USA.
South Med J. 2004 Mar;97(3):319-21. doi: 10.1097/01.SMJ.0000054501.05278.5F.
We describe the case of a patient in whom anticonvulsant hypersensitivity syndrome developed during treatment with phenytoin and progressed when therapy was changed to phenobarbital. Although therapeutic options remain controversial, corticosteroids and IV immunoglobulin were used in our patient. The patient had a complete recovery, suggesting the potential benefit of corticosteroids and IV immunoglobulin for anticonvulsant hypersensitivity syndrome.
我们描述了一名患者的病例，该患者在使用苯妥英钠治疗期间发生了抗惊厥药超敏反应综合征，在改为使用苯巴比妥治疗时病情进展。尽管治疗方案仍存在争议，但我们的患者使用了皮质类固醇和静脉注射免疫球蛋白。患者完全康复，提示皮质类固醇和静脉注射免疫球蛋白对治疗抗惊厥药超敏反应综合征可能有益。
