Kadyan Vivek, Clinchot Daniel M, Colachis Sam C
Department of Physical Medicine and Rehabilitation, The Ohio State University Medical Center, Columbus, Ohio, USA.
Am J Phys Med Rehabil. 2004 Mar;83(3):191-7. doi: 10.1097/01.phm.0000113401.47681.a6.
To determine cost-effectiveness of surveillance with duplex ultrasound for thromboembolic disease in individuals with acute traumatic spinal cord injury at admission to rehabilitation.
In this retrospective sequential case series study, individuals with traumatic spinal cord injury admitted to our rehabilitation facility between July 1, 1988, and December 31, 1998, were identified. Cost at our institution for treatment of thromboembolic disease was tabulated in 2001-2002 dollar amounts. Using this cost information, in a statistical model founded on available medical evidence, analysis for cost-effectiveness was then performed.
A total of 369 subjects met inclusion criteria. Based on the statistical model, the cost and estimated mortality from thromboembolic disease per subject when performing admission duplex ultrasounds was $449.28 and 0.016%, respectively. The estimated total cost per subject when not performing admission duplex ultrasounds was $136.29, with predicted mortality of 0.524% due to thromboembolic disease. Therefore, cost of one life saved when performing admission duplex ultrasound surveillance is calculated to be $61,542, with cost per life year gained between $1193 and $9050, depending on age at time of injury and severity of injury.
Duplex ultrasound is a cost-effective tool for deep venous thrombosis surveillance in individuals with acute traumatic spinal cord injury admitted to rehabilitation programs.
确定在康复入院时,对急性创伤性脊髓损伤患者采用双功超声监测血栓栓塞性疾病的成本效益。
在这项回顾性序列病例系列研究中,确定了1988年7月1日至1998年12月31日期间入住我们康复机构的创伤性脊髓损伤患者。以2001 - 2002年美元金额列出了我们机构治疗血栓栓塞性疾病的费用。利用这些成本信息,在基于现有医学证据的统计模型中,进行成本效益分析。
共有369名受试者符合纳入标准。根据统计模型,入院时进行双功超声检查时,每名受试者因血栓栓塞性疾病的成本和估计死亡率分别为449.28美元和0.016%。不进行入院双功超声检查时,每名受试者的估计总成本为136.29美元,因血栓栓塞性疾病的预测死亡率为0.524%。因此,进行入院双功超声监测时挽救一条生命的成本计算为61,542美元,每获得一个生命年的成本在1193美元至9050美元之间,具体取决于受伤时的年龄和损伤严重程度。
双功超声是对入住康复项目的急性创伤性脊髓损伤患者进行深静脉血栓监测的一种具有成本效益的工具。