Charlesworth Brian, Barton Nick
Institute for Cell, Animal and Population Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK.
Curr Biol. 2004 Mar 23;14(6):R233-5. doi: 10.1016/j.cub.2004.02.054.
Genome sizes vary enormously. This variation in DNA content correlates with effective population size, suggesting that deleterious additions to the genome can accumulate in small populations. On this view, the increased complexity of biological functions associated with large genomes partly reflects evolutionary degeneration.
基因组大小差异极大。这种DNA含量的变化与有效种群大小相关，这表明基因组中有害的新增部分会在小种群中积累。据此观点，与大基因组相关的生物功能复杂性增加部分反映了进化退化。
