进化：稳定期的细菌突变

Evolution: bacterial mutation in stationary phase.

作者信息

Sniegowski Paul

机构信息

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

出版信息

Curr Biol. 2004 Mar 23;14(6):R245-6. doi: 10.1016/j.cub.2004.02.058.

DOI:10.1016/j.cub.2004.02.058

PMID:15043837

Abstract

A recent study indicates that the genomic mutation rate of the gut bacterium Escherichia coli is substantially higher in nongrowing than growing cultures. These findings are important in the light of the ongoing controversy over the generality and robustness of stationary phase mutagenesis and its evolutionary implications.

摘要

最近的一项研究表明，肠道细菌大肠杆菌的基因组突变率在非生长培养物中比在生长培养物中要高得多。鉴于目前关于稳定期诱变的普遍性和稳健性及其进化意义存在争议，这些发现具有重要意义。