Coulter David M
Division of Neonatology, Department of Pediatrics, The University of Utah School of Medicine, Salt Lake City, UT 84132-2202, USA.
J Perinatol. 2004 Mar;24(3):194-5. doi: 10.1038/sj.jp.7211031.
A 2-month-old premature infant developed a spontaneous chylothorax. Medical therapy (chest tube drainage, parenteral alimentation) and thoracic duct ligation at 103 days of age had no effect. Drainage ceased during an octreotide infusion. The effusion recurred after octreotide was stopped, and responded completely to a longer course of therapy. Octreotide offers a substantial advantage over current medical management to some babies with spontaneous chylothorax.
一名2个月大的早产儿发生了自发性乳糜胸。药物治疗(胸腔闭式引流、胃肠外营养)以及在103日龄时进行的胸导管结扎均无效。在注射奥曲肽期间胸腔引流停止。奥曲肽停用后积液复发,而在较长疗程的治疗后积液完全消退。对于一些患有自发性乳糜胸的婴儿,奥曲肽比目前的药物治疗具有显著优势。