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[胃癌患者表虚证型的病理研究]

[Pathology of syndrome-differentiation types of superficial deficiencies in patients with gastric cancer].

作者信息

Cui T J, Lin Q C

机构信息

Fujian College of TCM, Fuzhou.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Mar;12(3):151-3, 132.

PMID:1504533
Abstract

Analysing the relations between TCM syndrome differentiation type and pathology in 312 patients with gastric cancer, the authors put forward the syndrome differentiation type of deficiency of vitality and excess in superficiality. The studies showed that the four syndrome types of deficiency of vitality such as Spleen-Stomach deficiency, Qi-Xue deficiency, Yin deficiency and inner heat, Spleen-Kidney Yang deficiency and the three syndrome types of excess in superficiality such as Liver-Stomach disorder, blood stasis and stagnation of Qi, Phlegm-dampness and stagnation of toxic. The same changes in pathologic characteristic of both were from early to late stage, the infiltration getting deeper, the tumor getting larger and the metastasis of lymph nodes around the stomach from little to much. Their difference was that in the deficiency of vitality syndrome-type, the chief manifestation was in nest or spread infiltration type which became serious by degrees, whereas in excess in superficiality type, the reaction of lymphoidocytes around the cancer was decreasing. The studies also showed that in most syndrome types of Spleen-Kidney Yang deficiency and Phlegm-dampness and stagnation of toxic, the tumor occurred in wide-range and the degree of tissue differentiation was quite low. The authors suggested that there might be morphopathologic basis in TCM syndrome differentiation types and the conclusion has practical value in guiding clinics.

摘要

通过对312例胃癌患者中医辨证类型与病理关系的分析,作者提出了本虚标实证的辨证类型。研究显示,本虚证的四种证型如脾胃虚弱、气血亏虚、阴虚内热、脾肾阳虚,标实证的三种证型如肝胃不和、血瘀气滞、痰湿毒蕴。二者病理特征的相同变化是从早期到晚期,浸润逐渐加深,肿瘤逐渐增大,胃周淋巴结转移由少到多。其不同之处在于本虚证型主要表现为巢状或弥漫浸润型,且程度逐渐加重,而标实证型癌周淋巴细胞反应逐渐减弱。研究还显示,在脾肾阳虚、痰湿毒蕴等多数证型中,肿瘤呈弥漫性发生,组织分化程度较低。作者认为中医辨证类型可能存在形态病理学基础,该结论对临床具有实际指导价值。

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