Ljungdahl Mikael, Eriksson Lars-Gunnar, Nyman Rickard, Gustavsson Sven
Kirurgkliniken, Akademiska sjukhuset i Uppsala.
Lakartidningen. 2004 Feb 26;101(9):768-72.
Peptic ulcer disease is the most common cause of acute haemorrhage from the upper gastrointestinal tract. Despite therapeutical improvements, the mortality rate remains high. Massive bleeding may, if haemostasis is not achieved by endoscopic treatment, require surgery. Often these patients are elderly with high comorbidity and, hence, are poor surgical candidates. We have therefore used angiography and selective arterial embolisation as an alternative option in 18 patients with massive ulcer bleeding. 13 patients were treated after failed endoscopic treatment, and 5 patients were treated for recurrent bleeding after previous emergency operations for bleeding ulcers. Embolisation of the arterial branch supplying the ulcer was possible in all patients. Permanent haemostasis was achieved in all but one patient, in whom the bleeding was controlled at an emergency operation. Our opinion is that angiographic embolisation is an effective way to control massive bleeding from peptic ulcers. In this way emergency operations in poor surgical candidates can be avoided.
消化性溃疡病是上消化道急性出血最常见的原因。尽管治疗方法有所改进,但死亡率仍然很高。如果内镜治疗无法实现止血,大量出血可能需要手术治疗。这些患者通常是老年人,合并症多,因此不是理想的手术候选者。因此,我们对18例大量溃疡出血患者采用血管造影和选择性动脉栓塞作为替代选择。13例患者在内镜治疗失败后接受治疗,5例患者在先前因出血性溃疡进行急诊手术后出现复发性出血而接受治疗。所有患者均可行溃疡供血动脉分支的栓塞。除1例患者在急诊手术中控制出血外,其余患者均实现了永久性止血。我们认为血管造影栓塞是控制消化性溃疡大出血的有效方法。通过这种方式,可以避免对手术风险高的患者进行急诊手术。