Saito Hitoshi, Tsuchida Akihiko, Hayashida Yasuharu, Takagi Makoto, Tamura Kazuhiko, Kawakita Hideaki, Kubouchi Takeo, Kinoshita Masao, Sato Shigeki, Kataba Yoshiaki, Aoki Tatsuya
Dept. of Surgery, Kosei Central Hospital.
Gan To Kagaku Ryoho. 2004 Mar;31(3):411-4.
A 65-year-old male was admitted to our hospital because of sudden onset of upper abdominal pain due to the perforation of gastric cancer with synchronous hepatic metastasis. He underwent total gastrectomy with lymphatic dissection of D1 + alpha. Pathological diagnosis of the surgical specimen was moderately differentiated tubular adenocarcinoma. The cancer progression was fStage IV (T1, N0, H1, P0). Since 50 days after surgery, he had received oral administration of UFT (300-600 mg/day) and intermittent intrahepatic arterial infusion of 5-FU (one injection, 500 mg/2 weeks). Seven months after the start of chemotherapy, the size of hepatic lesion was reduced. Thirteen months later, the tumor became necrotic with cystic change. Furthermore, 22 months later, abdominal CT scan showed complete response. He has been well without recurrence for 38 months following the start of chemotherapy.
一名65岁男性因胃癌穿孔伴同步肝转移导致上腹部突发疼痛而入住我院。他接受了D1+α淋巴结清扫的全胃切除术。手术标本的病理诊断为中分化管状腺癌。癌症分期为IV期（T1，N0，H1，P0）。术后50天起，他接受了UFT口服治疗（300 - 600毫克/天）以及肝动脉间歇性5 - FU灌注治疗（每次注射500毫克，每2周一次）。化疗开始7个月后，肝脏病变大小缩小。13个月后，肿瘤出现坏死并伴有囊性变。此外，22个月后，腹部CT扫描显示完全缓解。自化疗开始后38个月，他情况良好，无复发。
