Pang L, Eyzaguirre C
Department of Physiology, University of Utah School of Medicine, Salt Lake City 84108.
Brain Res. 1992 Mar 13;575(1):167-73. doi: 10.1016/0006-8993(92)90440-k.
Intracellular recordings were made from cultured glomus cells of rat carotid bodies. Hypoxia (PO2 1-61 Torr), induced by Na-dithionite (Na2S2O4), differentially affected cells that were clustered and those that were isolated. More than 80% of clustered cells depolarized and their input resistance decreased, whereas about 60% of isolated cells hyperpolarized and their input resistance increased. In both groups, the mechanisms for cell depolarization or hyperpolarization appeared similar. Differences between clustered and isolated cells seemed to be conditioned by the sustentacular cells. Their processes surrounded clustered cells but were absent around isolated ones. However, we may have also functionally different glomus cells which may or may not correspond to the different types described by anatomists.
从大鼠颈动脉体的培养球细胞进行细胞内记录。由连二亚硫酸钠（Na2S2O4）诱导的低氧（PO2 1 - 61托）对聚集的细胞和孤立的细胞产生不同影响。超过80%的聚集细胞去极化，其输入电阻降低，而约60%的孤立细胞超极化，其输入电阻增加。在两组中，细胞去极化或超极化的机制似乎相似。聚集细胞和孤立细胞之间的差异似乎受支持细胞的调节。它们的突起围绕着聚集细胞，但在孤立细胞周围不存在。然而，我们可能也有功能不同的球细胞，它们可能与解剖学家描述的不同类型相对应，也可能不对应。
