Hrncír Z
II. interní klinika lékarské fakulty Univerzity Karlovy, Hradec Králové.
Cas Lek Cesk. 1992 Jul 10;131(13):399-401.
In five previously not treated patients with active primary idiopathic polymyositis/dermatomyositis and severe dysphagia persisting for 3-8 weeks treatment with a series of 4-5 intravenous pulses a 1 g methylprednisolone was provided. In four patients dysphagia disappeared within 2-14 days, in one patient within 30 days marked improvement was recorded. During the 12-64-month follow up period in none of the patients relapse or deterioration of dysphagia was observed. One female patient died 12 months after establishment of the diagnosis during reactivation of the basic disease with marked fibrosis of the pulmonary interstitium, the remaining patients are in permanent remission.
在5例既往未接受治疗的活动性原发性特发性多肌炎/皮肌炎且严重吞咽困难持续3 - 8周的患者中，给予一系列4 - 5次静脉注射1g甲泼尼龙进行治疗。4例患者的吞咽困难在2 - 14天内消失，1例患者在30天内有明显改善。在12 - 64个月的随访期内，未观察到任何患者吞咽困难复发或恶化。1例女性患者在诊断确立12个月后，基础疾病复发且伴有明显的肺间质纤维化，最终死亡，其余患者均处于长期缓解状态。
