Dogru Murat, Honda Rie, Omoto Masahiro, Fujishima Hiroshi, Yagi Yukiko, Tsubota Kazuo, Kojima Takashi, Matsuyama Mie, Nishijima Saori, Yagi Yukiko
Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
J Cataract Refract Surg. 2004 Mar;30(3):558-65. doi: 10.1016/j.jcrs.2003.12.027.
To prospectively assess the clinical and visual outcomes of phacoemulsification and implantation of a rollable intraocular lens (IOL) with a thin optic and compare the results with those of implantation of a foldable acrylic IOL.
Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Ichikawa, Chiba, Japan.
Sixteen consecutive eyes of 8 patients (4 women, 4 men) with corticonuclear cataract had small-incision clear corneal phacoemulsification with implantation of a rollable ThinOptX IOL (ThinOptX Inc.) in the capsular bag. Twenty eyes of 10 age- and sex-matched patients (5 women, 5 men) with the same diagnosis had phacoemulsification and intracapsular implantation of an AcrySof foldable acrylic IOL (MA60BM, Alcon). The patients' refractive status and uncorrected and best corrected distance visual acuities were assessed preoperatively and 1 week and 1, 3, and 6 months after surgery. The uncorrected and best corrected near acuities were measured before and 6 months after surgery. Contrast visual acuity was measured with variable contrast charts 1, 3, and 6 months after surgery, and the results in the 2 IOL groups were compared. Anterior segment photography, intraocular pressure (IOP) measurement, specular microscopy, and fundoscopy were done before surgery and at 1, 3, and 6 months.
The final best corrected distance acuity was better than 20/25 in all eyes with a ThinOptX IOL and 18 eyes (90%) with an AcrySof IOL. The best corrected near acuity was better than 20/40 in 12 eyes (75%) and 14 eyes (70%), respectively. The mean contrast acuity with charts 2 and 3 was significantly higher in the ThinOptX group than in the AcrySof group at all examinations (P<.05). The final mean postoperative induced astigmatism was 0.06 diopter (D) +/- 0.50 (SD) and 0.25 +/- 0.68 D, respectively (P>.05). There were no differences in IOP or corneal endothelial cell density between the 2 groups at any examination. No intraoperative or postoperative complications occurred.
ThinOptX IOL implantation provided best corrected near and distance visual acuities comparable to those provided by the AcrySof IOLs. The significantly higher contrast acuities attained after implantation of the ThinOptX lens may be attributable to its ultrathin properties.
前瞻性评估超声乳化联合植入薄光学部可卷曲人工晶状体（IOL）的临床及视觉效果，并将结果与植入可折叠丙烯酸酯IOL的结果进行比较。
日本千叶县市川市市川综合医院东京齿科大学眼科。
8例（4例女性，4例男性）核性白内障患者的16只连续眼接受了小切口透明角膜超声乳化术，并在囊袋内植入了可卷曲的ThinOptX IOL（ThinOptX公司）。10例年龄和性别匹配、诊断相同的患者（5例女性，5例男性）的20只眼接受了超声乳化术，并在囊袋内植入了AcrySof可折叠丙烯酸酯IOL（MA60BM，爱尔康公司）。术前以及术后1周、1、3和6个月评估患者的屈光状态、未矫正和最佳矫正远视力。术前及术后6个月测量未矫正和最佳矫正近视力。术后1、3和6个月使用可变对比度图表测量对比敏感度视力，并比较两组IOL的结果。术前以及术后1、3和6个月进行眼前节照相、眼压（IOP）测量、角膜内皮细胞镜检查和眼底检查。
所有植入ThinOptX IOL的眼以及18只（90%）植入AcrySof IOL的眼最终最佳矫正远视力均优于20/25。最佳矫正近视力分别在12只（75%）和14只（70%）眼中优于20/40。在所有检查中，ThinOptX组使用图表2和3时的平均对比敏感度视力均显著高于AcrySof组（P<0.05）。最终术后平均诱导散光分别为0.06屈光度（D）±0.50（标准差）和0.25±0.68 D（P>0.05）。两组在任何检查中的IOP或角膜内皮细胞密度均无差异。未发生术中或术后并发症。
植入ThinOptX IOL后获得的最佳矫正近视力和远视力与植入AcrySof IOL相当。植入ThinOptX晶状体后获得的对比敏感度视力显著更高可能归因于其超薄特性。
