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[非复杂性择期胆囊切除术后的常规引流?一项前瞻性随机研究]

[Routine drainage following uncomplicated, elective cholecystectomy? A prospective, randomized study].

作者信息

Förster R, Schnabel M, Krahl M, Lindlar R, Rothmund M

机构信息

Klinik für Allgemeinchirurgie, Philipps-Universität Marburg.

出版信息

Chirurg. 1992 Jul;63(7):558-62.

PMID:1505264
Abstract

A prospective randomized and controlled study of prophylactic drainage after simple, elective cholecystectomy was carried out. From March 1988 to June 1991 80 patients received an Easy-Flow drain and 80 did not. Operation and perioperative management were standardized. The endpoint of the study was postoperative morbidity, especially postoperative pyrexia and subhepatic fluid collection. The latter was identified by ultrasonography performed daily on postoperative day 1-4. No patient died. The morbidity including postoperative pyrexia revealed no difference between drained and undrained patients. In 19 of the patients with (23.8%) and in 25 of the patients without drainage (31.3%) a subhepatic fluid collection could be demonstrated by ultrasonography. This difference was not statistically significant either. We conclude that prophylactic drainage after elective, simple cholecystectomy is of no use for the patient. As subhepatic fluid collections can be seen in drained as well as in undrained patients it has to be accepted that drainage does not guarantee the removal of subhepatic fluid. Therefore its indicatory function (bleeding) and the ability to prevent the patient having biliary peritonitis or local abscess has to be put in doubt.

摘要

开展了一项关于单纯择期胆囊切除术后预防性引流的前瞻性随机对照研究。1988年3月至1991年6月,80例患者置入了Easy-Flow引流管,80例未置入。手术及围手术期管理均标准化。研究终点为术后发病率,尤其是术后发热和肝下积液。术后第1 - 4天每天进行超声检查以确定肝下积液情况。无患者死亡。包括术后发热在内的发病率在置管引流组和未置管引流组之间无差异。超声检查显示,置管引流的患者中有19例(23.8%)出现肝下积液,未置管引流的患者中有25例(31.3%)出现肝下积液。这一差异也无统计学意义。我们得出结论,择期单纯胆囊切除术后预防性引流对患者并无益处。由于置管引流和未置管引流的患者均可见肝下积液,因此必须承认引流并不能保证清除肝下积液。因此,其指示功能(出血)以及预防患者发生胆汁性腹膜炎或局部脓肿的能力值得怀疑。

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