Ukkola O
Department of Internal Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland.
J Endocrinol Invest. 2004 Jan;27(1):96-8. doi: 10.1007/BF03350918.
Appetite is controlled by a complicated system with hunger and satiety signals interacting in complex pathways both peripherally and centrally. Insulin, leptin and ghrelin are key hormonal regulators of food intake. Ghrelin enhances appetite while leptin is a satiety signal. A novel peripheral regulator of food intake, peptide YY(3-36), is released from the gastrointestinal tract postprandially. In this review old and new peripheral signals and their interaction in the control of food intake are briefly discussed.
食欲由一个复杂的系统控制,饥饿和饱腹感信号在周围和中枢的复杂途径中相互作用。胰岛素、瘦素和胃饥饿素是食物摄入的关键激素调节因子。胃饥饿素增强食欲,而瘦素是一种饱腹感信号。一种新型的食物摄入外周调节因子,肽YY(3-36),在餐后从胃肠道释放。在这篇综述中,简要讨论了新旧外周信号及其在食物摄入控制中的相互作用。