Toyokura Minoru, Fujii Chieko, Urano Tetsuya, Nishiya Kenzo, Ishida Akira
Department of Rehabilitation Medicine, Tokai University Oiso Hospital, Nakagun, Kanagawa, Japan.
Tokai J Exp Clin Med. 2003 Oct;28(3):97-101.
We reported a patient who developed acute quadriplegic myopathy (AQM) following treatment with a combination of high-dose steroid and nondepolarizing blocking agent for idiopathic interstitial pneumonia (IIP). Few cases of AQM with IIP have been reported in the literature. The HP progressed rapidly in our patient, but the high-dose steroid therapy was effective. The rehabilitative intervention comprised of passive range-of-motion exercise, functional training, and muscle strengthening. After the initial presentation with severe weakness, the AQM gradually improved and the patient regained full physical function in 8 months. The clinical course was almost identical to that of AQM patients with other lung diseases. Though unlikely to influence the improvement of muscle weakness in AQM patients, the lung diseases associated with AQM may require specific consideration in determining suitable rehabilitation programs and observing patients before and after full recovery from dysmobility.
我们报告了一名特发性间质性肺炎（IIP）患者，其在接受高剂量类固醇和非去极化阻滞剂联合治疗后发生了急性四肢瘫性肌病（AQM）。文献中报道的AQM合并IIP的病例很少。我们的患者中HP进展迅速，但高剂量类固醇治疗有效。康复干预包括被动关节活动度训练、功能训练和肌肉强化训练。在最初表现为严重肌无力后，AQM逐渐改善，患者在8个月内恢复了全部身体功能。临床过程与患有其他肺部疾病的AQM患者几乎相同。尽管不太可能影响AQM患者肌无力的改善，但与AQM相关的肺部疾病在确定合适的康复计划以及观察患者从运动障碍完全恢复前后的情况时可能需要特殊考虑。
