口腔副球孢子菌病还是鳞状细胞癌？

Oral paracoccidioidomycosis or squamous cell carcinoma?

作者信息

Kaminagakura Estela, Graner Edgard, de Almeida Oslei Paes, Di Hipolito Júnior Osvaldo, Lopes Marcio Ajudarte

机构信息

Department of Oral Diagnosis, Dental School, University of Campinas, Piracicaba-SP, Brazil.

出版信息

Gen Dent. 2004 Jan-Feb;52(1):48-50.

PMID:15055671

Abstract

Paracoccidioidomycosis is a deep, systemic, and progressive mycosis caused by Paracoccidioides brasiliensis. Oral lesions normally are multiples with a mulberry-like appearance. This article reviews an unusual case involving a chronic, solitary, and ulcerated lesion whose clinical aspects were similar to squamous cell carcinoma. Viewed microscopically, the lesion showed pseudoepitheliomatous hyperplasia and non-necrotizing granulomas. The patient was treated with systemic ketoconazole. Over the next 11 years, follow-up examinations were performed but no recurrence was observed.

摘要

副球孢子菌病是一种由巴西副球孢子菌引起的深部、全身性、进行性真菌病。口腔损害通常为多发性，呈桑葚样外观。本文报道了1例罕见病例，患者表现为慢性、孤立性溃疡性损害，临床特征类似于鳞状细胞癌。显微镜下观察，损害显示假上皮瘤样增生和非坏死性肉芽肿。患者接受了全身性酮康唑治疗。在接下来的11年中，进行了随访检查，未观察到复发。