Oral chemical erosion can be caused by several factors. The most significant and most frequent is gastroesophageal reflux disease (GERD). Asymptomatic patients with GERD often are unaware that they may have a potential life-threatening condition. The dental profession is in a position to identify the subtle oral signs of the disease and has the obligation to be alert to the signs of gastroesophageal reflux, making appropriate referrals when necessary. The purpose of this article is to raise awareness concerning earlier detection of the subtleties of chemical erosion, particularly from GERD. A severe case of asymptomatic chemical erosion caused by GERD is presented.