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Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?

作者信息

Bell Ian M

机构信息

Merck Research Laboratories, WP14-2, P.O. Box 4, Sumneytown Pike, West Point, PA 19486, USA.

出版信息

J Med Chem. 2004 Apr 8;47(8):1869-78. doi: 10.1021/jm0305467.

DOI:10.1021/jm0305467
PMID:15055985
Abstract
摘要

相似文献

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Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?法尼基转移酶抑制剂：癌症化疗的合理方法？
J Med Chem. 2004 Apr 8;47(8):1869-78. doi: 10.1021/jm0305467.
2
Farnesyltransferase inhibitors: an overview of the results of preclinical and clinical investigations.法尼基转移酶抑制剂：临床前和临床研究结果概述
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Farnesyltransferase inhibitors.法尼基转移酶抑制剂
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Farnesyltransferase inhibitors.法尼基转移酶抑制剂
Cancer Chemother Biol Response Modif. 2002;20:151-67.
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Farnesyltransferase inhibitors: targeting the molecular basis of cancer.法尼基转移酶抑制剂：针对癌症的分子基础
Biochim Biophys Acta. 1999 May 31;1423(3):C19-30. doi: 10.1016/s0304-419x(99)00007-4.
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Farnesyltransferase inhibitors as anticancer agents: current status.法尼基转移酶抑制剂作为抗癌剂：现状
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Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer.他汀类药物和法尼基转移酶抑制剂对癌症发生发展的影响。
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Ras farnesyltransferase inhibition: a novel and safe approach for cancer chemotherapy.Ras法尼基转移酶抑制：一种用于癌症化疗的新型安全方法。
Acta Pharmacol Sin. 2000 May;21(5):396-404.
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Farnesyltransferase inhibitors: antineoplastic properties, mechanisms of action, and clinical prospects.法尼基转移酶抑制剂：抗肿瘤特性、作用机制及临床前景。
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Farnesyltransferase inhibitors as anticancer agents: critical crossroads.法尼基转移酶抑制剂作为抗癌药物：关键转折点。
Curr Opin Drug Discov Devel. 2004 Jul;7(4):478-86.

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Novel route to chaetomellic acid A and analogues: serendipitous discovery of a more competent FTase inhibitor.
新型 chaetomellic 酸 A 及其类似物的合成途径：法尼基转移酶抑制剂的意外发现。
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