一名患有先天性体液免疫缺陷的8岁女孩患f型流感嗜血杆菌脑膜炎。

Meningitis due to Haemophilus influenzae type f in an 8-year-old girl with congenital humoral immunodeficiency.

作者信息

Fickweiler K, Borte M, Fasshauer M, Spencker F-B, Handrick W, Rodloff A C

机构信息

Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Liebigstrasse 24, D-04103, Leipzig, Germany.

出版信息

Infection. 2004 Apr;32(2):112-5. doi: 10.1007/s15010-004-3040-1.

DOI:10.1007/s15010-004-3040-1

PMID:15057576

Abstract

We report on an 8-year-old Haemophilus influenzae type b-vaccinated girl with meningitis due to H. influenzae type f. The girl had an oro-facio-digital syndrome and a hypogammaglobulinemia, obviously predisposing the patient to invasive infections. Treatment with cefotaxime was successful.Incidence, predisposing factors and the influence of H. influenzae type b immunization on invasive infections with non-type b H. influenzae strains in children are discussed.

摘要

我们报告了一名8岁接种过b型流感嗜血杆菌疫苗的女孩，她因f型流感嗜血杆菌感染患脑膜炎。该女孩患有口面指综合征和低丙种球蛋白血症，显然这使她易患侵袭性感染。头孢噻肟治疗成功。文中讨论了儿童中f型流感嗜血杆菌侵袭性感染的发病率、易感因素以及b型流感嗜血杆菌免疫接种对非b型流感嗜血杆菌菌株侵袭性感染的影响。