James B J, Sullivan D M
Department of Radiation Oncology, Stanford University School of Medicine, CA 94305.
IEEE Trans Biomed Eng. 1992 Aug;39(8):845-51. doi: 10.1109/10.148392.
In the field of deep regional hyperthermia cancer therapy, the BSD-2000 Hyperthermia System is one of the most widely used devices. Because of the complexity of the treatment process, computer modeling has long been viewed as a desirable means of planning patient treatments. Patient-specific, three-dimensional computer modeling for treatment planning in the BSD-2000 has been in clinical use at this institution for two years. Two of the persistent problems have been the large amount of time needed to create the patient model from a computed tomography (CT) scan (one and a half days), and the lack of a way to view the large amounts of data that comprise the output of a treatment plan, i.e., the specific absorption rate (SAR) at 20,000 to 30,000 cells. Here we present a method that obtains the dielectric properties needed for hyperthermia treatment planning directly from the CT image with minimum operator interaction, a process which takes about a half day and is more accurate. Comparison is made with the previous method of drawing contours around the different tissue types. We further describe a method which displays the output as iso-SAR contours directly over the CT scan of the patient.
在深部区域热疗癌症治疗领域，BSD - 2000热疗系统是使用最为广泛的设备之一。由于治疗过程的复杂性，长期以来计算机建模一直被视为规划患者治疗的理想手段。针对BSD - 2000进行的特定患者三维治疗规划计算机建模已在本机构临床应用两年。一直存在的两个问题是，从计算机断层扫描（CT）创建患者模型所需时间较长（一天半），以及缺乏查看构成治疗计划输出的大量数据的方法，即20000至30000个细胞处的比吸收率（SAR）。在此，我们提出一种方法，该方法通过最少的操作员交互直接从CT图像获取热疗治疗规划所需的介电特性，这一过程大约需要半天时间且更准确。将其与之前在不同组织类型周围绘制轮廓的方法进行了比较。我们还进一步描述了一种方法，该方法可将输出显示为直接覆盖在患者CT扫描图像上的等SAR轮廓。
