Nikkanen Heikki E, Burns Michele M
Division of Emergency Medicine-Medical Toxicology, Department of Medicine, Children's Hospital, Boston, Massachusetts, USA.
Pediatrics. 2004 Apr;113(4):927-9. doi: 10.1542/peds.113.4.927.
We describe an occupational exposure to hydrogen sulfide gas in a 16-year-old boy. While cleaning the reoxygenation tank of a fish hatchery, he and an adult supervisor lost consciousness. The adult died, and the adolescent regained consciousness briefly when emergency medical services personnel administered oxygen. At a local emergency department, he was intubated for respiratory distress. He was transferred to a tertiary care facility for additional management and, over the next 2 weeks, had a recovery to normal function. Hydrogen sulfide is a colorless, malodorous gas that results from the decay of organic material. It is a byproduct of industry and agriculture. The mechanism of its toxicity is related primarily to inhibition of oxidative phosphorylation, which causes a decrease in available cellular energy. Although there is some anecdotal evidence to suggest that the early use of hyperbaric oxygen is beneficial, supportive care remains the mainstay of therapy. This report highlights the sources of exposure, management, and need for more stringent application of safety regulations in industries in which adolescents are employed.
我们描述了一名16岁男孩职业性接触硫化氢气体的情况。在清理一个鱼苗孵化场的再充氧罐时，他和一名成年监管人员失去了意识。那名成年人死亡，而这名青少年在紧急医疗服务人员给予氧气后短暂恢复了意识。在当地的急诊科，他因呼吸窘迫而接受了气管插管。他被转至一家三级护理机构接受进一步治疗，在接下来的两周内恢复了正常功能。硫化氢是一种无色、有恶臭的气体，由有机物质腐烂产生。它是工农业的副产品。其毒性机制主要与抑制氧化磷酸化有关，这会导致细胞可用能量减少。尽管有一些传闻证据表明早期使用高压氧有益，但支持性治疗仍然是主要的治疗方法。本报告强调了接触源、管理以及在雇佣青少年的行业中更严格执行安全法规的必要性。
