Shaposhnikov M V, Zaĭnullin V G, Belogolov I N
Institute of Biology Ural Division, Russian Academy of Sciences, Syktyvkar, 167982 Russia.
Radiats Biol Radioecol. 2004 Jan-Feb;44(1):15-7.
It has been analyzed the frequency of the recessive lethal mutations in the unirradiated X-chromosome of Drosophila. Females of wild type (CS) as well as of error-prone (mei-41) and error-free (mus209) mutant strains were used. In CS hybrids the increasing of the mutation rate (p < 0.05) was found. In muc209 hybrids the mutation rate was not affected. In mei-41 hybrids the tendency to decreasing of the mutation rate was found. The obtained results demonstrate the possible role of error-prone repair in the inducing of mutations in the unirradiated X-chromosome in the presence of irradiated homologue.
已经分析了果蝇未受辐射的X染色体中隐性致死突变的频率。使用了野生型（CS）以及易出错（mei-41）和无差错（mus209）突变株的雌性果蝇。在CS杂种中发现突变率增加（p < 0.05）。在muc209杂种中，突变率未受影响。在mei-41杂种中发现了突变率下降的趋势。所得结果表明，在存在受辐射同源物的情况下，易出错修复可能在未受辐射的X染色体中诱导突变中发挥作用。
