[暴露于20 cGyγ射线后小鼠组织中的Bcl-2凋亡调节蛋白]
[Bcl-2 apoptosis regulating proteins in mouse tissues after exposure to 20 cGy of gamma-radiation].
作者信息
Pushkareva N B, Sorokina N I, Koterov A N, Nikol'skiĭ A V, Filippovich I V
机构信息
State Research Center-Institute of Biphysics, Ministry of Public Health of Russian Federation, Moscow, 123182 Russia.
出版信息
Radiats Biol Radioecol. 2004 Jan-Feb;44(1):23-6.
PMID:15060935
Abstract
A pronounced increase of Bcl-2 content was observed in thymus of mice exposed to 20 cGy of gamma-radiation 1 and 24 hours after the exposure; six days after the exposure the bcl-2 content lowered to the control one. No changes in bcl-2 level were revealed in mice liver during the period of observation. A level of Bax protein was stable in mice thymus during 60 days of observation.
摘要
在暴露于20 cGyγ射线后1小时和24小时的小鼠胸腺中，观察到Bcl-2含量显著增加；暴露后六天，bcl-2含量降至对照水平。在观察期内，小鼠肝脏中bcl-2水平未发现变化。在60天的观察期内，小鼠胸腺中Bax蛋白水平稳定。
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